St George's, University of London
- Start Date: 06 Feb, 2023
- 3 weeks
- Study Content: Videos
Learn the principles and language of genomic variant interpretation and enhance your working knowledge of the ACMG guidelines.
Course Fee: Free
Certificate Cost: See Fees and Eligibility
Course Description
This course is made available through the eLearnAfrica and FutureLearn partnership.
Discover the principles of genetic variant interpretation
Our individual genomes make us unique, and contribute to both rare and common disease.
In genomic testing, it’s vital to distinguish the clinically relevant, disease-causing variant from its background normal genomic variation in order to safely manage patients.
Get variant interpretation training for effectively managing patients
This course is designed to educate health professionals involved in the variant journey from the laboratory to the patient.
You’ll explore the fundamental principles of variant interpretation and review the American College of Clinical Genetics and Genomic (ACMG) and The Association for Clinical Genomic Science (AGCS) guidelines. You will also take a detailed look at the tools available to aid genomic variant interpretation.
Study the ACMG and ACGS guidelines in theory and practice
The ACMG and ACGS guidelines were developed to promote consistency in the tools used to classify a genomic variant as pathogenic, likely pathogenic, likely benign, benign, or uncertain.
You’ll explore how the ACMG evaluated each of the tools and applied a weighting, as well as the algorithm developed to combine the evidence from each of these tools.
You’ll be encouraged to apply your learning through workshopped examples that illustrate both the strengths and weaknesses of the ACMG tools and framework.
This course is part of a series with Interpreting Genomic Variation: Inherited Cancer Susceptibility.
This course is designed for all health professionals who require knowledge of the basic principles of variant interpretation and applying ACMG guidelines.
This may include:
- genomic specialists leading on variant interpretation
- clinical scientists
- clinical geneticists
- genomic counsellors
It will also be useful for genomic champions, eg the clinical specialist who will be attending multi-disciplinary genomic variant interpretation meetings and will need to understand the principles and language of genomic variant interpretation.
Certificate cost may vary. You will be redirected to the host page for cost and payment options.
St George's, University of London
St George’s is the UK’s only university dedicated to medical and health sciences education, training and research.
The university provides a world-class multi-professional health sciences education that equips graduates to meet today’s healthcare needs through relevant scientific research, clinical excellence, strong interpersonal skills and team-based working. Sharing a clinical environment with a major London teaching hospital, its innovative approach to education results in well-rounded, highly skilled clinicians, scientists, and health and social care professionals.
St George’s has more than 250 years of excellence and innovation in research and education resulting in groundbreaking advances in medicine and healthcare. Alumni include Edward Jenner, John Hunter, Muriel Powell and Patrick Steptoe. The university has three research institutes focus on biomedical and scientific discovery, advancing the prevention and treatment of disease in the fields of population health, heart disease and infection - three of the greatest challenges to global health in the 21st century.
This institution is available on eLearnAfrica through partnership with FutureLearn.
COLLABORATION POLICY
By enrolling in a course on or through eLearnAfrica, you are joining a special worldwide community of learners. The aspiration of eLearnAfrica is to provide anyone with an internet connection access to courses from the best universities and institutions in the world and to provide our learners the best educational experience internet technology enables. You are a part of the community that will help eLearnAfrica achieve this goal. eLearnAfrica depends upon your motivation to learn the material and to do so with honesty and academic integrity. In order to participate in eLearnAfrica, you must agree to the Honor Code below and any additional terms specific to a class.
ELEARNAFRICA HONOR CODE PLEDGE
By enrolling in a course, program, or degree hosted on the eLearnAfrica App or Site, I agree that I will:
-
Complete all tests and assignments on my own, unless collaboration on an assignment is explicitly permitted.
-
Maintain only one user account and not let anyone else use my username and/or password.
-
Not engage in any activity that would dishonestly improve my results, or improve or hurt the results of others.
-
Not post answers to problems that are being used to assess student performance.
-
Abide by any and all requirements of the eLearnAfrica Participants as may regard the expectations of civil or academic behavior or of community standards.
VIOLATIONS
If you are found in violation of the Terms and Conditions or Honor Code, you may be subject to one or more of the following actions:
-
Receiving a zero or no credit for an assignment;
-
Having any certificate earned in the course withheld or revoked;
-
Being unenrolled from a course, learning program or degree program; or
-
Termination of your use of the App and/or Site.
-
Additional actions may be taken at the sole discretion of eLearnAfrica and eLearnAfrica course providers.
No refunds will be issued in the case of any corrective action for such violations.
Honor code violations will be determined at the sole discretion of eLearnAfrica, the Partners, or Members. You will be notified if a determination has been made that you have violated this honor code and you will be informed of the corresponding action to be taken as a result of the violation.
CHANGING THE HONOR CODE
Please note that we review and may make changes to this Honor Code from time to time. Any changes to this Honor Code will be effective immediately upon posting on this page, with an updated effective date. By accessing the App and/or Site after any changes have been made, you signify your agreement on a prospective basis to the modified Honor Code and any changes contained therein. Be sure to return to this page periodically to ensure familiarity with the most current version of this Honor Code.
Effective Date: September 22, 2016